Cold Outreach That Gets Replies

I want to reach out to people at companies I'm interested in, but I don't have any direct connections. Help me craft cold outreach that actually gets responses.

Ask me about the company I'm targeting, the role I'm interested in, who I want to reach, which platform I'll use, and what I know about the person. Also ask about my background and why I'm genuinely interested in this company. Then help me:

1. Write a short, personalized message that doesn't feel templated
2. Create a compelling subject line (for email) or opening hook (for LinkedIn)
3. Explain the psychology of why this approach works
4. Provide variations for different scenarios (no job posted vs. specific job opening)
5. Craft a follow-up message if they don't respond
6. Determine optimal timing and frequency for outreach
7. Handle common objections or non-responses gracefully

I want to be persistent without being annoying or desperate.